5-氟脲嘧啶
产品名称： 5-氟脲嘧啶
英文名称： 5-Fluorouracil
产品编号： F6627
产品价格： 0
产品产地： sigma
品牌商标： sigma
更新时间： null
使用范围： null
上海复申生物科技有限公司
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产品名称
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Biochem/physiol Actions
A potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. It is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-FU leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.
包装
1, 5, 10 g in glass bottle
性质
| Related Categories | Antitumor Agents, Apoptosis and Cell Cycle,Bioactive Small Molecules, Cancer Research, Cell Biology, |
| assay | ≥99% (HPLC) |
| form | powder |
| color | white |
| mp | 282-286 °C (dec.)(lit.) |
| solubility | 1 M NH4OH: soluble |
| DMSO/DMF: soluble | |
| methanol: soluble | |
| Gene Information | human ... TYMS(7298) |