Overview

Product name
Anti-CD18 antibody [CLB-LFA-1/1, 54] (FITC)

See all CD18 products (43) ...


Description
Mouse monoclonal [CLB-LFA-1/1, 54] to CD18 (FITC)


Conjugation
FITC


Conjugation notes
The antibody is conjugated with fluorescein isothiocyanate isomer 1 (FITC). The molecular F/P ratio is between 5 and 10.


Specificity
ab51573 is directed against the CD18 antigen (Lymphocyte Function-associated Antigen 1, integrin beta 2 chain), which is expressed on mature immunocompetent lymphocytes and their neoplastic counterparts, granulocytes and monocytes. It is absent in patients with LAD1.


Tested applications
Flow Cytmore details


Cross reactivity
 
Reacts with
Human
 


Immunogen


Peripheral blood lymphocytes of a T gamma lymphocytosis patient (Human)



Properties

Form
Liquid


Storage instructions
Store at +4°C in the dark. Do not freeze.


Storage buffer
Preservative: 0.1% Sodium Azide

Constituents: 1% (w/v)BSA, 20mM Tris, 150mM Sodium chloride, pH 8.0


Concentration

 


    
100tests at mg/ml



Purity
Ion Exchange Chromatography


Purification notes
The antibody was purified from ascites using column chromatography


Primary antibody notes
The monoclonal antibody can be used to detect LFA1/MO1 deficiency in patients suffering from recurrent bacterial infections.


Clonality
Monoclonal


Clone number
CLB-LFA-1/1, 54


Myeloma
Sp2/0


Isotype
IgG1

http://www.abcam.com/CD18-antibody-CLB-LFA-1-1-54-FITC-ab51573.html