FITC标记的磷酸化微管相关蛋白4抗体-抗体-抗体-生物在线
FITC标记的磷酸化微管相关蛋白4抗体

FITC标记的磷酸化微管相关蛋白4抗体

商家询价

产品名称： FITC标记的磷酸化微管相关蛋白4抗体

英文名称： Anti-phospho-MAP4(Ser941)/FITC

产品编号： HZ-5438R-FITC

产品价格： null

产品产地： 中国/上海

品牌商标： HZbscience

更新时间： 2023-08-17T10:24:20

使用范围： IF=1:50-200

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 Rabbit Anti-phospho-MAP4(Ser941)/FITC Conjugated antibody

FITC标记的磷酸化微管相关蛋白4抗体

 

英文名称 Anti-phospho-MAP4(Ser941)/FITC
中文名称 FITC标记的磷酸化微管相关蛋白4抗体
别    名 MAP4 (phospho S941); p-MAP4 (phospho S941); MAP4(phospho S941); DKFZp779A1753; MAP-4; MAP4; MAP4_HUMAN; MGC8617; Microtubule associated protein 4; Microtubule-associated protein 4; OTTHUMP00000210723; OTTHUMP00000210725; OTTHUMP00000210727; OTTHUMP00000210730.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 细胞生物  信号转导  细胞周期蛋白  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 121kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human MAP4 around the phosphorylation site of Ser941
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The MAP4 (Microtubule associated protein 4)is a non neuronal microtubule associated protein. It promotes microtubule assembly.The phosphorylation of the Pro rich region in the C-terminus negatively regulates MAP4 activity to promote microtubule assembly.

Function:
Non-neuronal microtubule-associated protein. Promotes microtubule assembly. 

Subunit:
Interacts with SEPT2; this interaction impedes tubulin-binding.

Subcellular Location:
Cytoplasm, cytoskeleton. 

Post-translational modifications:
Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Phosphorylation on Ser-787 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 3 is phosphorylated on Ser-337 and Ser-338. 

Similarity:
Contains 4 Tau/MAP repeats. 

Database links:
UniProtKB/Swiss-Prot: P27816.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application
   

MAP4（微管相关蛋白4）是一种非神经元微管相关蛋白。它促进微管组装，C-末端富含脯氨酸区域的磷酸化负调控MAP4活性，促进微管组装。