FITC标记的MBLAC2蛋白抗体
产品名称： FITC标记的MBLAC2蛋白抗体
英文名称： Anti-MBLAC2/FITC
产品编号： HZ-18706R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-MBLAC2/FITC Conjugated antibody
FITC标记的MBLAC2蛋白抗体
| 英文名称 | Anti-MBLAC2/FITC |
| 中文名称 | FITC标记的MBLAC2蛋白抗体 |
| 别 名 | DKFZp686P15118; MBLAC2; MBLC2_HUMAN; Metallo beta lactamase domain containing protein 2; Metallo-beta-lactamase domain-containing protein 2; MGC46734. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MBLAC2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: MBLAC2 is a 279 amino acid protein that belongs to the glyoxalase II family and metallo-β-lactamase superfamily. Existing as two alternatively spliced isoforms, MBLAC2 binds two zinc ions and is encoded by a gene that maps to human chromosome 5q14.3. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. Database links: Entrez Gene: 153364 Human SwissProt: Q68D91 Human Unigene: 64004 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
MBLAC2是属于乙醛酸酶II家族和金属β-内酰胺酶超家族的279个氨基酸。MBLAC2作为两个可选择的剪接异构体存在，结合两个锌离子，并且由映射到人类染色体5q14.3的基因编码。第5染色体包含1亿8100万个碱基对，并包含人类基因组的近6%。5号染色体通过ERCC8基因与Cockayne综合征相关，家族性腺瘤性息肉病通过APC抑癌基因与腺瘤性息肉病相关。Treacher Collins综合征也是5号染色体相关的，是由TCOF1基因内的插入或缺失引起的。5号染色体p臂缺失导致Cri du chat综合征，而q臂或5号染色体缺失在治疗相关的急性髓细胞白血病和骨髓增生异常综合征中很常见。