KITLG (N-term) Peptide
产品名称： KITLG (N-term) Peptide
英文名称： KITLG (N-term) Peptide
产品编号： P0472
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of KITLG.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human KITLG.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Early myeloid cells expressing c-KIT isoforms differ in signal transduction, survival and chemotactic responses to Stem Cell Factor.
Young SM, Cambareri AC, Odell A, Geary SM, Ashman LK.Cell Signal. 2007 Dec;19(12):2572-81. Epub 2007 Aug 15.
- 2.
- Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis.
Pick M, Azzola L, Mossman A, Stanley EG, Elefanty AG.Stem Cells. 2007 Sep;25(9):2206-14. Epub 2007 Jun 7.
- 3.
- Stem cell factor/c-kit receptor signaling enhances the proliferation and invasion of colorectal cancer cells through the PI3K/Akt pathway.
Yasuda A, Sawai H, Takahashi H, Ochi N, Matsuo Y, Funahashi H, Sato M, Okada Y, Takeyama H, Manabe T.Dig Dis Sci. 2007 Sep;52(9):2292-300. Epub 2007 Apr 5.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis of KITLG (arrow) using KITLG polyclonal antibody (Cat # PAB1883). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the KITLG gene (Lane 2) (Origene Technologies).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with KITLG polyclonal antibody (Cat # PAB1883) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 4254
- Protein Accession#:
- NP_000890;P21583
- Gene Name:
- KITLG
- Gene Alias:
- DKFZp686F2250,KL-1,Kitl,MGF,SCF,SF,SHEP7
- Gene Description:
- KIT ligand
- Omim ID:
- 184745
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- mast cell growth factor,steel factor,stem cell factor
- Interactome
