分子量:76 kDa

纯度:>92% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Biotinylated Human Transferrin R by the LAL method.

Buffer:PBS, pH7.4

生物活性:Measured by its binding ability in a functional ELISA.Immobilized Human Transferrin, His Tag (Cat# TRN-H4229) at 10 μg/mL (100 L/well),can bind Biotinylated Human Transferrin R (Cat# TFR-H8243) with a linear range of 2-200 ng/mL.

产品特性:Biotinylated Human Transferrin R / CD71 Protein  has a calculated MW of 76 kDa. The predicted N-terminus is Cys 89. As a result of glycosylation, the reducing (R) protein migrates as 80-85 kDa in SDS-PAGE.

产品背景:CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.