FITC标记的细胞色素c氧化酶亚型2抗体-抗体-抗体-生物在线
FITC标记的细胞色素c氧化酶亚型2抗体

FITC标记的细胞色素c氧化酶亚型2抗体

商家询价

产品名称: FITC标记的细胞色素c氧化酶亚型2抗体

英文名称: Anti-MTCO2/Cytochrome c oxidase subunit 2/FITC

产品编号: HZ-2376R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-MTCO2/Cytochrome c oxidase subunit 2/FITC Conjugated antibody 

FITC标记的细胞色素c氧化酶亚型2抗体

 

英文名称 Anti-MTCO2/Cytochrome c oxidase subunit 2/FITC
中文名称 FITC标记的细胞色素c氧化酶亚型2抗体
别    名 Cytochrome c oxidase polypeptide II; MT-CO2; COII; COXII; MTCO2; COX2; Cytochrome c oxidase II; Cytochrome c oxidase subunit 2; COX2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  转录调节因子  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cytochrome c oxidase subunit 2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.

Function:
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.

DISEASE:
Defects in MT-CO2 are a cause of mitochondrial complex IV deficiency (MT-C4D) [MIM:220110]; also known as cytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patients manifest Leigh syndrome.

Similarity:
Belongs to the cytochrome c oxidase subunit 2 family.

Database links:

Entrez Gene: 4513 Human

Omim: 516040 Human

SwissProt: P00403 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

细胞色素C氧化酶是催化氧还原为水的呼吸链的一个组成部分。亚基1-3形成酶复合物的功能核心。亚基2通过细胞色素C通过双核铜中心转移到催化亚基1的双金属中心。